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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AKT3
All Species:
28.48
Human Site:
T445
Identified Species:
52.22
UniProt:
Q9Y243
Number Species:
12
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y243
NP_005456.1
479
55775
T445
E
F
T
A
Q
T
I
T
I
T
P
P
E
K
Y
Chimpanzee
Pan troglodytes
XP_512662
481
55720
T449
E
F
T
A
Q
S
I
T
I
T
P
P
D
R
Y
Rhesus Macaque
Macaca mulatta
XP_001104624
604
69574
T570
E
F
T
A
Q
T
I
T
I
T
P
P
E
K
Y
Dog
Lupus familis
XP_547496
479
55710
T445
E
F
T
A
Q
T
I
T
I
T
P
P
E
K
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q9WUA6
479
55696
T445
E
F
T
A
Q
T
I
T
I
T
P
P
E
K
Y
Rat
Rattus norvegicus
Q63484
479
55778
T445
E
F
T
A
Q
T
I
T
I
T
P
P
E
K
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513899
512
59226
A483
Y
F
D
E
E
F
T
A
Q
T
I
T
I
T
P
Chicken
Gallus gallus
Q6U1I9
432
48872
D404
N
S
I
G
Q
S
P
D
S
I
L
I
T
A
S
Frog
Xenopus laevis
Q98TY9
481
56023
T449
E
F
T
A
Q
M
I
T
I
T
P
P
D
Q
D
Zebra Danio
Brachydanio rerio
Q7ZTW4
433
48964
D405
N
S
I
G
C
S
P
D
S
A
L
V
T
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8INB9
611
68466
E563
E
F
T
G
E
S
V
E
L
T
P
P
D
P
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q17941
541
62181
Q490
E
F
T
S
Q
P
V
Q
L
T
P
P
S
R
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
P87253
1142
127954
S1112
N
F
D
S
E
F
T
S
V
T
P
V
L
T
P
Conservation
Percent
Protein Identity:
100
77.7
78.6
99.5
N.A.
99.5
99.1
N.A.
86.1
40.2
82.9
41.5
N.A.
51.3
N.A.
51.9
N.A.
Protein Similarity:
100
88.7
79.1
100
N.A.
99.7
99.3
N.A.
87.3
55.3
90.8
56.7
N.A.
62.6
N.A.
67.6
N.A.
P-Site Identity:
100
80
100
100
N.A.
100
93.3
N.A.
13.3
6.6
73.3
0
N.A.
40
N.A.
46.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
93.3
N.A.
20
13.3
86.6
6.6
N.A.
73.3
N.A.
73.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
21
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
30
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
46.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
54
0
0
0
8
0
8
0
0
0
8
0
% A
% Cys:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
16
0
0
0
0
16
0
0
0
0
24
0
16
% D
% Glu:
70
0
0
8
24
0
0
8
0
0
0
0
39
0
0
% E
% Phe:
0
85
0
0
0
16
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
24
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
16
0
0
0
54
0
54
8
8
8
8
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
39
0
% K
% Leu:
0
0
0
0
0
0
0
0
16
0
16
0
8
0
0
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
24
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
8
16
0
0
0
77
70
0
8
16
% P
% Gln:
0
0
0
0
70
0
0
8
8
0
0
0
0
8
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
16
0
% R
% Ser:
0
16
0
16
0
31
0
8
16
0
0
0
8
8
24
% S
% Thr:
0
0
70
0
0
39
16
54
0
85
0
8
16
16
8
% T
% Val:
0
0
0
0
0
0
16
0
8
0
0
16
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
39
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _